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m6A Monoclonal antibody 說明書

更新時間:2024-08-23      點擊次數(shù):216

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m6A(N6-甲基腺苷)是哺乳動物 mRNA 中豐富的內(nèi)部修飾。這種修飾由 m6A 甲基轉(zhuǎn)移酶或稱 “寫手"(如 METTL3 和 METTL14)完成,并可由作為 “擦除器 "的去甲基化酶(如 FTO 和 ALKBH5)逆轉(zhuǎn)。m6A 修飾的 mRNA 的穩(wěn)定性受 m6A 閱讀蛋白 YTHDFs 的調(diào)節(jié),YTHDFs 可識別 m6A 并降低目標轉(zhuǎn)錄本的穩(wěn)定性。

產(chǎn)品性質(zhì)

 targets m6A in WB, IHC, IF, IP, RIP, Dot Blot, ELISA applications and shows reactivity with m6A, Human, Mouse, Rat samples.

Tested ApplicationsRIP, IHC, ELISA, Dot Blot Application Description
Cited ApplicationsWB, IHC, IF, IP, RIP
Tested Reactivitym6A, Human, Mouse, Rat
Cited Reactivityhuman, mouse, rat, pig, monkey
ImmunogenCompound 
Host / IsotypeMouse / IgG3
ClassMonoclonal
TypeAntibody
Full Namem6A
Synonyms6-N-Methyladenoside, m6A, N6-methyladenosine
GenBank Accession Numberm6A
Gene Symbol
Gene ID (NCBI)
RRIDAB_2918796
ConjugateUnconjugated
FormLiquid
Purification MethodProtein A purification
Storage BufferPBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
貨號品名規(guī)格品牌
78DA10019m6A Monoclonal antibody50 µLBIOHUB


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